Ppv npv chart
PPV is the probability that the disease is present given a positive test result, and is defined as: PPV = * (1 )*(1) * S S S Sensitivity specificity Sensitivity Similarly, the NPV is the probability that the disease is absent given a negative test result, and is defined as: NPV = S S S *(1 ) (1 )* *(1 ) Specificity sensitivity Specificity PPV is now 18 %, whereas NPV is 98 %. As expected, PPV decreased due to the decrease of the disease prevalence, whereas at the same time NPV increased. A PPV of 18 % means that out of 100 subjects who have positive test results, there will be only 18 who actually have the disease. Study outcomes included one or more of sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) (Table 2). Six of the 12 studies included only patients with a negative or uncertain history of varicella 8 , 10 - 14 so only the negative predictive value, and not the positive predictive value, could be determined.